Effect of low calcium

Total serum calcium concentration: the term \' <8mg/DL (<2mmol/L), <7mg/DL in preterm infants (<1.75mmol/L); can also be based on the use of experimental method (type of electrodes) with calcium ion concentration to determine; Ca++<3.0~4.4mg/dl (<0.75~1.10mmol/L).

Neonatal intensive care neonatal hypocalcemia rather common in indoor, high risk groups include preterm infants, small for gestational age infant, newborn infants of diabetic mother, a history of perinatal asphyxial neonates.

The etiology of

Early hair low centurium blood syndrome of causes is does not clearly (occurs in health Hou number hours within), some in preterm infants or illness of newborn, in health Hou appears temporarily sexual relative parathyroid function low, dang by placenta continued supply of ion calcium suddenly interrupt, they of serum calcium decline. this role in diabetes mother or parathyroid function with hyperthyroidism mother of newborn in the increased, because in pregnancy period, these women of ion calcium level than normal; such was born Shi newborn parathyroid cannot normal of maintained normal serum calcium level. in other newborn, kidney obvious lack on parathyroid of reaction and phosphate of urine liquid. Wai during perinatal period asphyxia also can led drop calcium pigment level increased, it can suppression calcium from bones release and led low calcium blood syndrome.

With late-onset hypocalcemia (3rd after a health) rare, usually because the baby was fed a high phosphate-bearing load caused by milk or formula, with increased serum phosphate cause hypocalcemia.

Finally, a very small number of parathyroid dysfunction babies can have long-term effects of low calcium, especially seen in DiGeorge syndrome, the babies can have aortic anomaly, unusual facies, cell immunodeficiency and parathyroid gland dysfunction.

Symptoms, signs, and diagnosis

Newborn low calcium blood syndrome usually is no symptoms of, but they can performance for muscle tension low, respiratory suspended, into milk difference, upset disturbed, hand tetany or convulsion, and low blood glucose syndrome and withdrawal drug comprehensive syndrome has similar of symptoms; ECG Shang QT time of extended prompted low calcium blood syndrome. low calcium blood syndrome of signs rarely occurs, unless serum total calcium <7mg/DL (1.75mmol/L) or ion calcium <3.0mg/DL. in late hair low calcium blood syndrome, is greater than 3rd of newborn performance for hand tetany or convulsion.

The treatment of

Early hair low calcium blood Syndrome often in number days recovered, no symptoms of newborn low calcium blood syndrome usually does not need treatment. newborn serum calcium level >7mg/DL (1.75mmol/L) or ion calcium >3.5mg/DL rarely need treatment. those serum calcium level <7mg/DL (1.75mmol/L) of newborn need 10% glucose acid calcium solution treatment, 200mg/kg (10% glucose acid calcium solution 2ml/kg), slow vein lost Note 30 minutes above, each ml 10% glucose acid calcium solution contains 100mg glucose acid calcium and 9mg element calcium. had fast lost note can caused heart had sustained, so in lost note Shi to monitoring heart rate. must tight observation vein infusion parts, because calcium solution penetration into organization has irritation, and can caused local organization injury. in fast corrected low calcium blood syndrome Hou, glucose acid calcium can mixed Yu other vein rehydration in the continues to lost note. began Shi given glucose acid calcium 400mg/(kg.d), if need can gradually increased to 800mg/(kg.d), to prevent low calcium blood syndrome of recurrence. Dang began by mouth feeding Shi, can in formula milk in the joined also dose of glucose acid calcium; if need, can will 10% glucose acid calcium joined formula milk in the, this usually only need using number day.

With late-onset hypocalcemia, therapeutic purposes add adequate calcium is a formula, so that the ratio of calcium and phosphate Molarity is 4:1, which prompted the formation of calcium phosphate in gastrointestinal, to prevent intestinal absorption of PO4, promote intestinal calcium absorption.