1, hepatitis b surface antigen (HBSAG) is hepatitis b virus (HBV) particles of shell part, made up of protein. Is 2-6 months after hepatitis b virus infection, alanine aminotransferase 2-4 week appear before. Duration is less than 6 months acute, chronic duration greater than 6 months. Clinical and inspection of enzyme immunoassay and Radioimmunoassay method.
Normal reference values: negative
Clinical significance, because hepatitis b surface antigen is HBV coat protein, nucleic acid components do not contain viruses, itself is not infectious, does not reflect the severe acute respiratory syndrome virus has no replication, the replication process, strong or weak and prognosis of tendencies. Therefore, their clinical significance of combined with other checks you want comprehensive judgement. Positive, seen in chronic HBSAB carriers incubation period, acute hepatitis b, chronic persistent hepatitis and chronic active hepatitis, cirrhosis, and so on.
2, hepatitis b surface antibody (HBSAB) is a patient was infected with the hepatitis b virus (HBV), hepatitis b surface antigen protein antibody immune response generated by (protective antibodies), lasting several years. Description body for hepatitis b virus has a certain immunity. Enzyme ImmunoAssay and Radioimmunoassay method for clinical testing.
Normal reference values: negative
Clinical significance: positive, in hepatitis b, previously living with hepatitis b virus, and after the injection of hepatitis b vaccine, immunoglobulin HBSAB.
3, hepatitis b e Antigen (HBEAG) is a soluble protein of hepatitis b virus core particles, as one of the signs of hepatitis b viral replication, represented the infectious level-positive then the infectious good. And HBSAG at the same time or later appear, acute duration is less than 10 weeks, chronic duration greater than 10 weeks. Enzyme ImmunoAssay and Radioimmunoassay method for clinical testing.
Normal reference values: negative
Clinical significance: positive, seen in acute hepatitis b, chronic hepatitis, cirrhosis, and so on. In addition, both HBSAG and HBEAG-positive pregnant women babies born, 80%~100% would be affected by hepatitis b virus infection.
4, b-hepatitis e antibody (HBEAB) appears after the HBEAG negative turn, represents the infectious decline, but still has certain infectious, and suggests that a longer course. Enzyme ImmunoAssay and Radioimmunoassay method for clinical testing.
Normal reference values: negative
Clinical significance: positive, seen in chronic hepatitis b (48. 3%), liver cirrhosis (68. 3%), liver (80%). In addition, HBEAB-positive pregnant women have 20% in infants born to infected with hepatitis b virus.
5, the hepatitis b core antibody (HBCAB) is hepatitis b core Antigen stimulation produced by the liver cells of immune globulin, is HBV antibody antibodies appear earlier in the system, often following the HBSAG, appears after HBEAG, b does not protect, infectious, and continued in the period of acute and chronic infections. Enzyme ImmunoAssay and Radioimmunoassay method for clinical testing.
Normal reference values: negative
Clinical significance: positive, seen in acute hepatitis b, chronic hepatitis b, hepatitis b virus carriers and a history of previous infection.
Body\'s infection with the hepatitis b virus (HBV) can occur after an appropriate immune response, form the corresponding Antigen, antibodies. Major hepatitis b e Antigen (HBCAG), hepatitis b core antibody (HBCAB). due to hepatitis b core Antigen in the serum is not easy to check out the \' clinical addition to the core Antigen collectively, the \"two half of hepatitis b\". The result should be comprehensive judgment.
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