3/9/11

What drugs will make contraceptive failure

Affect the contraceptive drug has the effect of the following categories:


Antibiotics: rifampicin, tetracycline and other tetracycline class penicillin, ampicillin, and other classes;


Anticonvulsants: phenobarbital, of phenobarbital, Primidone, carpipramine, ethosuximide etc;


Antifungal medicines: effects of griseofulvin.


These drugs reduce the efficacy of steroid contraceptives mechanisms, mainly through the following link: affected liver enzyme metabolism; improving the activity of the sex hormone binding globulin; reducing intestinal bacteria levels.


If you use a steroid contraceptives at the same time, and requires the use of these drugs should be how to deal with it?


If using oral contraceptives, while the short-term use of these drugs, you can add volume taking contraceptives, by taking 2 tablets at a time; if the short-term use of antibiotics in the treatment, vaginal spotting, should be by taking birth control pills.


Contraceptive effect weakened, sometimes also taking other drugs and the use of contraceptives is high doses or low-dose-related. If the use of oral contraceptives in the first half of the cycle when using low dose oral contraceptives with other drugs or, more likely to make contraceptive failure.


In General, the effect of low dose oral contraceptives are more vulnerable to other drugs, current trends are oral contraceptives reduce the dose, or use small doses of drug delivery system, such as progesterone subcutaneous implants or simple low-dose oral contraceptive tablets, but in China, production of oral contraceptives in the early part of the low-dose tablets. Therefore, the interaction between oral contraceptives with other drugs, should be paid close attention of the majority of women of childbearing age.

No comments:

Post a Comment